神經外科

兒童神經外科,神經外科,神經脊椎外科

神經外科專科
外科專科
神經加護證照
外科重症證照
一般醫學教育教師
OSCE國考考官

林口長庚醫院副教授級醫師
部定助理教授
加拿大Western Hospital 神經病理科進修
美國加州大學舊金山分校 (UCSF)幹細胞研究

現任：林口長庚醫院主治醫師
經歷：基隆長庚，嘉義長庚主治醫師

腦瘤治療研究
腦下垂體腺瘤內視鏡手術
頸椎腰椎手術
癲癇治療
手汗手術

International Referred Journals (SCI)
1. Hunag YC, Chuang HL, Cheng CN and Scott RM. Membranous obstruction of fourth ventricle outlet. Pediatric Neurosurg, 35(1):43-7, July, 2001. (SCI: 0.967, Surgery, 103/148=69.5%)
2. Liao CC, Lui TN, Chen LR, Chuang CC, Huang YC. Spinal cord injury without radiological abnormality in preschool-aged children: correlation of magnetic resonance imaging findings with neurological outcomes. J Neurosurg 2005 July; 103(1suppl): 17-23 (SCI: 2.124; surgery 42/148=28.3%)
3. Yang ST, Huang YC, Chuang CC, Hsu PW. Traumatic internal carotid artery dissection. J Clin Neurosci. 2006 Jan; 13(1):123-8.Surgery (SCI: 1.19 Clinical Neurology 121/156=77.6%)
4. Chuang CC, Chang CN, Wei KC, Hsu PW, Huang YC, Chen YL, Lai LJ, Pai PC. Surgical treatment fir severe visual compromised patients after pituitary apoplexy. J Neurooncol. 2006 Apr 28.(SCI:2.323; Clinical Neurology 70/156=44.8%)
5. Huang YC, Tseng CK, Chang CN, Wei KC, Liao CC, Hsu PW. LINAC radiosurgery for intracranial cavernous malformation: 10-year experience. Clin Neurol Neurosurg. 2006 May 13 (SCI: 1.323; Surgery: 80/148=54.1%)
6. Huang YC, Tan HY, Jung HM, Chuang WY, Chuang CC, Hsu PW, Chang CN. Spinal Epidural Rosai-Dorfman Disease Preceding by Relapsing Uveitis: A Case Report with Literature Review. Spinal Cord. 2007 Jan 16.(SCI:2.071; Clinical Neurology 79/156=50.6%)
7. Lim DA, Huang YC, Alvarez-Buylla A. The adult neural stem cell niche: lessons for future neural cell replacement strategies. Neurosurg Clin N Am. 2007 Jan;18(1):81-92.(SCI:1.158; Surgery 86/148=58.1%)
8. Hsu PW, Chang CN, Tseng CK, Wei KC, Wang CC, Chuang CC, Huang YC*. Treatment of Epileptogenic Cavernomas: Surgery versus Radiosurgery. Cerebrovasc Dis. 2007 May 23;24(1):116-120 (SCI:3.041; Clinical Neurology 41/156=26.2%)
9. Yang TC, Lo YL, Huang YC, Yang ST. Traumatic anterior cerebral artery aneurysm following blunt craniofacial trauma. Eur Neurol 2007: 58(4):239-45. (SCI: 1.897; Clinical Neurology 84/156=53.8)
10. Lim DA*, Huang YC* ,Swigart T, Mirick AL, Jose Verdugo JMG, Wysocka J,Earnst P,Alvarez-Bulla A. Chromatin remodeling factor Mll specifies neurogenesis from postnatal brain neural stem cells. Nature. 2009 Mar 26;458(7237):529-33. *equally contributed to this paper.(IF 38.597, multiple dispiline 1/56)
11. Chen CC, Hsu PW, Erich Wu TW, Lee ST, Chang CN, Wei KC, Chuang CC, Wu CT, Lui TN, Hsu YH, Lin TK, Lee SC, Huang YC*. Stereotactic brain biopsy: Single center retrospective analysis of complications. Clin Neurol Neurosurg. 2009 Sep 16. (SCI: 1.323; Surgery 80/148=54.1%)
12. Hsu PW, Chang CN, Lee ST, Huang YC, Chen HC, Wang CC, Hsu YH, Tseng CK, Chen YL, Wei KC. Outcomes of 75 patients over 12 years treated for acoustic neuromas with linear accelerator-based radiosurgery. J Clin Neurosci. 2010 Mar 12. (SCI: 1.19, Clinical Neurology 121/156, 77.6%)
13. Chen CP, Wong AM, Hsu CC, Tsai WC, Chang CN, Lin SC, Huang YC, Chang CH, Tang SF. Ultrasound as a Screening Tool for Proceeding With Caudal Epidural Injections. Arch Phys Med Rehabil. 2010 Mar;91(3):358-363. (SCI: 2.159, Rehabilitation, 3/28=10.7%)
14. Hsu PW, Chen HC, Huang YC, Hsu CC, Wu T, Chang CN. Electrocorticographic monitoring as an alternative tool for the pre-surgical evaluation of patients with bi-temporal epilepsy. Chang Gung Med J. 2010 Mar-Apr;33(2):194-200.
15. Huang YC,Wei KC, Chang CH, Yang JT, Ho JT, Shen CC, Su CF, Cho DY, Chen GJ, Lin CW, Lee EJ, Wu JJ, Tsai MT, Chang CK, Huang TY, Chang CN. Neuro-oncological care system under the universal health insurance program in Taiwan: a retrospective survey of malignant gliomas. J Clin Neurosci. 2011 Jun;18(6):784-8. (SCI: 1.19, Clinical Neurology 121/156, 77.6%)
16. Chang CN, Huang YC, Yang DM, Kikuta K, Wei KJ, Kubota T, Yang WK.
A phase I/II clinical trial investigating the adverse and therapeutic effects of a postoperative autologous dendritic cell tumor vaccine in patients with malignant glioma. J Clin Neurosci. 2011 Aug;18(8):1048-54. (SCI: 1.19, Clinical Neurology 121/156, 77.6%)
17. Chuang CC, Chen E, Huang YC, Tu PH, Chen YL, Pai PC. Surgical outcome of oculomotor nerve palsy in pituitary adenoma. J Clin Neurosci. 2011 Nov;18(11):1463-8. Epub 2011 Sep 14. (SCI: 1.19, Clinical Neurology 121/156, 77.6%)
18. Tsai HC, Wei KC, Tsai CN, Huang YC, Chen PY, Chen SM, Lu YJ, Lee ST. Effect of valproic acid on the outcome of glioblastoma multiforme. Br J Neurosurg. 2012 Jun;26(3):347-54. (IF: 1.137, surgery, 139/199, 69.8%)
19. Huang HL, Yeh CN, Chang KW, Chen JT, Lin KJ, Chiang LW, Jeng KC, Wang WT, Lim KH, Chen CG, Lin KI, Huang YC, Lin WJ, Yen TC, Yu CS. Synthesis and evaluation of [18F]Fluorobutyl ethacrynic amide: a potential PET tracer for studying glutathione transferase. Bioorg Med Chem Lett. 2012 Jun 15;22(12):3998-4003.(IF: 2.554, medicinal chemistry, 23/57, 45.6%)
20. Cheng CC, Hsu PW, Lee ST, Chang CN, Wei KC, We CT, Hsu YH, Lin TK, Lee SC, Huang YC. Brain Surgery in Patients with Liver Cirrhosis. J Neurosurg. 2012 Aug;117(2):348-53. doi: 10.3171/2012.4.JNS111338. (IF 3.148, surgery, 21/199, 10.5%)
21. Huang YC, Chiang LW, Chang KS, Su WC, Lin YH, Jeng KC, Lin KI, Liao KY, Huang HL, Yu CS. Synthesis of Amino Core Compounds of Galactosyl Phytosyl Ceramide Analogs for Developing iNKT-Cell Inducers. Molecules. 2012 Mar 12;17(3):3058-81. (IF: 2.386, medicinal chemistry, 24/57, 42.1%)
22. Lee SC, Wang YC, Huang YC, Tu PH, Lee ST. Decompressive surgery for malignant middle cerebral artery syndrome. Journal of Clinical Neuroscience, 2013 Jan;20(1):49-52 (IF: 1.19, Clinical Neurology 121/156, 77.6%)
23. Huang HL, Yeh CN, Lee WY, Huang YC, Chang KW, Lin KJ, Tien SF, Su WC, Yang CH, Chen JT, Lin WJ, Fan SS, Yu CS. [123I]Iodooctyl fenbufen amide as a SPECT tracer for imaging tumors that over-express COX enzymes. Biomaterials
Volume 34, Issue 13, April 2013, Pages 3355–3365. (IF 7.404, engineer, biomedical, 2/79, 2.5%)
24. Yang HW, Hua MY, Hwang TL, Lin KJ, Huang CY, Tsai RY, Ma CC, Hsu PH, Wey SP, Hsu PW, Chen PY, Huang YC, Lu YJ, Yen TC, Feng LY, Lin CW, Liu HL, Wei KC. Non-invasive synergistic treatment of brain tumors by targeted chemotherapeutic delivery and amplified focused ultrasound-hyperthermia using magnetic nanographene oxide. Adv Mater. 2013 Jul 12;25(26):3605-11. (IF: 14.829, material sciences/ multidiscipline,7/241, 2.9%)
25. Zheng YC, Jung SM, Lee ST,Chang CN, Wei KC, Hsu YH, Wu CT, Liao CC, Lin CL, Lu YU, Hunag YC. Adult Supratentorial Extra-pineal Primitive Neuro-ectodermal Tumors. Journal of Clinl Neurosci, 2013 Volume 20, Issue 1, Pages 49-52. (IF: 1.253, clinical neurology 144/191, 75.3%)
26. Zheng YC, Jung SM, Chang WC, Huang YC. Primary Intramedullary Melanoma- A Case Report and review of literature, Chirurgia 2013 December;26(6):407-9 (IF: 0.517, surgery 165/198, 83.3% )
27. Liao HI, Wang CC, Wei KC, Chang CN, Hsu YH, Lee ST, Huang YC, Chen HC, Hsu PW. Fractionated stereotactic radiosurgery using the Novalis system for the management of pituitary adenomas close to the optic apparatus. J Clin Neurosci. 2013 Sep 28. (SCI: 1.19, Clinical Neurology 121/156, 77.6%)
28. Lin TK, Hsieh TC, Tsai HC, Lu YJ, Lin CL, Huang YC. Factors associated with poor outcome in patients with major intraoperative rupture of intracranial aneurysm.
Acta Neurol Taiwan. 2013 Sep;22(3):106-11.
29. Chen CC, Huang YC, Lee ST, Chen JF, Wu CT, Tu PH. Long-term result of vocal cord paralysis after anterior cervical disectomy. Brit J Neurosurg. 2014 Mar, Volume 23, Issue 3, pp 622-626 (SCI: 2.133, Orthopediatrics 19/65=29.2%)
30. *Huang HL, *Huang YC, Lee WY, Yeh CN, Lin KJ, Yu CS. 18F-Glutathione Conjugate as a PET Tracer for Imaging Tumors that Overexpress L-PGDS Enzyme. P
PLoS One. 2014; 9(8): e104118. Published online 2014 August 11. *co-1st author.
doi: 10.1371/journal.pone.0104118 (SCI: 3.534, multidiscipline: 8/55: 14.5%),
31. Huang YC, Wei KC, Chang CN, Chen PY, Hsu PW, Chen CP, Lu CS, Wan HL, Gutmann DH, Yeh TH. Transglutaminase 2 expression is increased as a function of malignancy grade and negatively regulates cell growth in meningioma. PLOSO ONE Published: September 23, 2014. DOI: 10.1371/journal.pone.0108228 (SCI: 3.534, multidiscipline: 8/55: 14.5%)
32. Huang YC, Shih HY, Sheng-Jia Lin, Chiu CC, Ma TL, Yeh TH, Cheng YC
The epigenetic factor Kmt2a/Mll1 regulates neural progenitor proliferation and neuronal and glial differentiation. Developmental Neurobiology 8 OCT 2014. doi: 10.1002/dneu.22235
33. Cheng YC, Chiang MC, Shih HU, Ma TL, Yeh TH, Huang YC, Lin CY, Lin SJ. The transcription factor hairy/E(spl)-related 2 induces proliferation of neural progenitors and regulates neurogenesis and gliogenesis. Developmental Neurobiology. doi:10.1016/j.ydbio.2014.10.018
34. Chiu CC, Yeh TH, Lai SC, Wu-Chou YH, Chen CH, Mochly-Rosen D, Huang YC, Chen YJ, Chen CL, Chang YM, Wang HL, Lu CS. Neuroprotective effects of aldehyde dehydrogenase 2 activation in rotenone-induced cellular and animal models of parkinsonism. Exp Neurol. 2014 Sep 28. pii: S0014-4886(14)00299-4. doi: 10.1016/j.expneurol.2014.09.016
35. Huang YC, Huang HL, Yeh CN, Lin KJ, Yu CS. Investigation of brain tumors using 18F-fluorobutyl ethacrynic amide and itsmetabolite with positron emission tomography. Oncotarget and Therapy. Jul 2015 V2015:8, page 1877-1885, DOI: http://dx.doi.org/10.2147/OTT.S78404.
36. Hsu CL, Kuo YC, Huang Y, Huang YC, Lui KW, Chang KP, Lin TL, Fan HC, Lin AC, Hsieh CH, Lee LY, Wang HM, Li HP, Chang YS. Application of a patient-derived xenograft model in cytolytic viral activation therapy for nasopharyngeal carcinoma. Oncotarget (Received: July 09, 2015; Accepted: September 11, 2015; Published: September 24, 2015) DOI:10.18632/oncotarget.5544

Doctorate thesis:
Huang YC. Chromatin remodeling factor Mll1 is essential for neurogenesis from postnatal neural stem cell.

Book Chapter
Huang YC, Hsu PW. Chapter: Linear accelerator radiosurgery for cavernous malformation. Tumors of the central nervous system, Volume 9. 2012

在林口長庚訓練後，目前在長庚主要在臨床及研究方面著力